Bet-hedging and communication in E. coli
The E. coli lac operon has been shown to display bistability after induction with the gratuitous inducers IPTG and TMG. The project aims at elucidating whether lactose can also evoke bistable expression of the lac operon. Possible benefits of such an induction patters are going to be investigated. In addition, the effect of the important intracellular second messanger cAMP in bistable gene expression will be analysed and we want to investigate if extracellular cAMP represents a signal at the population level.
References:
Contact details:
|
Dr. Katja Bettenbrock MPI für Dynamik komplexer technischer Systeme Experimentelle Systembiologie Sandtorstrasse 1 D-39106 Magdeburg Tel.: +49-(0)391 6110249 Fax: +49-(0)391 6110510  bettenbrock@mpi-magdeburg.mpg.deHomepage Link |
|
Dr. Ilka Bischofs-Pfeifer Universität Heidelberg Bacterial Signaling Networks (BQ 0041) BIOQUANT - room 602 Im Neuenheimer Feld 267 D-69120 Heidelberg Tel.: +49-(0)6221 54 51 365 Fax.:+49-(0)6221 54 51 487 ilka.bischofs@bioquant.uni-heidelberg.deHomepage Link |